IAG Cargo is adding transatlantic capacity with three flights a week between Barcelona and Miami, operated by LEVEL.
China Cargo Airlines has picked Worldwide Flight Services (WFS) to handle freighter services to Miami, which will start in January.
Congestion at major airports has put the spotlight on hubs who can provide specialised, freighter-friendly services.
Travel restrictions have been lifted and capacity is flooding back on to the vital transatlantic sector as the world comes out of the pandemic.
Miami International Airport has broken cargo records for a second year running by handling 2.7 million tons in 2021.
FedEx Express has completed a major expansion at Miami International Airport, increasing capacity for services to Latin America and the Caribbean.
DHL Express has spent $78m doubling capacity at its Americas Hub at Miami International Airport.
American Airlines Cargo will be providing direct services from London Heathrow to nine key US cities from November.